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Also known as
CFLAR
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Other names
CASP8 and FADD-like apoptosis regulator isoform 6; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; usurpin beta; caspase homolog; inhibitor of FLICE; caspase-eight-related protein; MACH-related inducer of toxicity; FADD-like anti-apoptotic molecule; FADD-like antiapoptotic molecule 1; caspase-related inducer of apoptosis; cellular FLICE-like inhibitory protein; caspase-like apoptosis regulatory protein; CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; Usurpin
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CFLAR
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Gene name synonims
N/A
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Other gene names
CFLAR; CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASH; CASP8AP1; CLARP; MRIT; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT
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Clonality
Monoclonal
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Immunoglobulin isotype
Mouse IgG3 heavy chain and kappa light chain.
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Clone
P5D8AT
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
CFLAR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
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Form Appearance
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
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Concentration
N/A
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Storage and shipping
For periods up to 1 month Store the antibody at +4 degrees Celsius., for longer periods of time, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Prevent freeze thaw cycles. Stability: 12 months the antibody should be stored at -20 degrees Celsius.. 1 month at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable.
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Tested applications
ELISA (EIA), Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. This 1 is suited for programmed cell-death studies.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
FADD, CASP8
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Short name
Mouse Anti- CASP8 FADD-like apoptosis regulator Antibody
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Technique
anti-Human, apoptosis, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, apoptosis pathway, mouses
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Host
mouse
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Species
Human, Humans, Mouses
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Alternative name
Anti-Mouse Anti Human CASP8 and FADD-like apoptosis regulator
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Alternative technique
celldeath, antibodies, murine
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Alternative to gene target
Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
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