anti-CYP3A7 Antibody
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Catalog number29-646
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PricePlease ask
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Size100 ug
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Gene infoCYP3A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
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Gene namesCYP3A7, CP37, P450-HFLA, CYPIIIA7
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by protein A chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP3A7.
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Immuno applicationELISA, Western Blot
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Antibody adviceCYP3A7 antibody can be used for detection of CYP3A7 by ELISA at 1:312500. CYP3A7 antibody can be used for detection of CYP3A7 by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store CYP3A7 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr262290932
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Ncbi nrNP_000756
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KDa57 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr1551
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GENE symbolCYP3A7
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Antigene namecytochrome P450, family 3, subfamily A, polypeptide 7
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SourceHomo sapiens
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Protein nrP24462
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCYP3A7-CYP3A51P, CYP3A7
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Short nameanti-CYP3A7 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toCYP3A7 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameCYP3A7-CYP3A51P readthrough
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Locus
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Discovery year2015-01-19
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 3 subfamily A member 7
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Synonyms gene name
- cytochrome P450, subfamily IIIA, polypeptide 7
- cytochrome P450, family 3, subfamily A, polypeptide 7
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-09-14
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Entrez gene record
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Pubmed identfication
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Classification
- Cytochrome P450 family 3
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
