IL-1 alpha, murine recombinant
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Catalog number
4126-1000
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Price
Please ask
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Size
1 mg
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Synonyms
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
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Alternative_names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
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Description
Activates TNF-α and plays a critical role in immune response regulation
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥98%
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Assay
SDS-PAGE
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Purity
≥98%
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Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells was found to be < 0.01ng/ml, corresponding to a specific activity of 1 x 108 IU/mg.
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Results
< 0.01ng/ml,
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Molecular Weight
18.0 kDa
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Storage Temp
-20°C
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Shipping
Gel pack
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Shelf Life
12 months
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Appearance
Lyophilized protein
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Physical form description
Lyophilized after extensive dialysis against PBS
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Reconstitution Instructions
Reconstitute in H₂O to a concentration of not less than 100 µg/ml. which can then be diluted into other aqueous solutions.
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Background Information
Recombinant mouse Interleukin-1 alpha (IL-1α) produced in E. coli is a non-glycosylated polypeptide chain containing 156 amino acids and has a molecular weight of 18 kDa. Murine IL-1α is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional description
The IL-1 alpha, murine recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
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Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
IL1A, IL1B, IL1F10, IL36B, IL36A, IL19, IL17F, IL36G, IL25, IL22
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Short name
IL-1 alpha, murine recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Interleukin-1 a, murine Rec.
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
interleukin 1 alpha
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 1 beta
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 beta
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 8 (eta)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 alpha
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 6 (epsilon)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 19
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2000-03-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 17F
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-03-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 25
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-26
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Methods or procedures used to obtain samples of URINE.
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Tree numbers
- E01.370.225.998.762
- E05.200.998.762
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
Product images
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