Phospho-SHP-2 (Tyr580) Antibody

Type

primary antibody
Shipping

Ice bag
Antigen

Phospho-SHP-2 (Tyr580)
Reactivity

Human,Mouse,Rat
Clonality

Polyclonal
Application

WB,IHC,IF/ICC,ELISA
Application_advice

WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Epitope

Phospho Tyr580
Immunogen

A synthesized peptide derived from human SHP-2 around the phosphorylation site of Tyrosine 580.
Purification

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Format

Liquid
Concentration

1mg/ml
Fragment

Fab fragment
Storage_Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Specificity

Phospho-SHP-2 (Tyr580) Antibody detects endogenous levels of SHP-2 only when phosphorylated at Tyrosine 580.
GendID

5781
Gene

PTPN11
GeneAlias

PTPN11 PTP2C SHPTP2
Unigene

Hs.506852;
Swiss Prot

Q06124
Weight

72kDa
Datasheet
Msds
Properties

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation

anticorps

Gene target

Phospho-SHP-2 Tyr580
Gene symbol

PTPN11, NR0B2, PTPN6, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
Short name

Phospho-SHP-2 (Tyr580) Antibody
Technique

Antibody, antibodies against human proteins, antibodies for
Host

Rabbit
Isotype

IgG
Alternative name

phosphorilated-SHP-2 (Tyr580) (antibody to-)
Alternative technique

antibodies

Identity

HGNC:9644
Gene

PTPN11
Long gene name

protein tyrosine phosphatase non-receptor type 11
Synonyms gene
- NS1
Synonyms gene name
- Noonan syndrome 1
- protein tyrosine phosphatase, non-receptor type 11
Synonyms
- BPTP3
- SH-PTP2
- SHP-2
- PTP2C
- SHP2
Synonyms name
- SH2 domain-containing protein tyrosine phosphatase 2
GenBank acession
- D13540
Locus

12q24.13
Discovery year

1993-03-03
Entrez gene record

5781
Pubmed identfication
- 7894486
- 1280823
Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
VEGA ID

OTTHUMG00000134334
Locus Specific Databases
- LRG_614

Identity

HGNC:9658
Gene

PTPN6
Long gene name

protein tyrosine phosphatase non-receptor type 6
Synonyms
- HCP
- HCPH
- PTP-1C
- SHP-1
- SHP1
Locus

12p13.31
Discovery year

1992-02-12
Entrez gene record

5777
Pubmed identfication
- 1639416
RefSeq identity
- NM_002831
Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
VEGA ID

OTTHUMG00000168518

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data