BAY 57-1293
-
Catalog number2556-25
-
PricePlease ask
-
Size25 mg
-
-
Alternative_nameN-methyl-N-(4-methyl-5-sulfamoylthiazol-2-yl)-2-(4-(pyridin-2-yl)phenyl)acetamide
-
DescriptionBAY 57-1293 is a potent helicase primase inhibitor. It inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57-1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. BAY 57-1293 has been shown to be a more effective agent than acyclovir (Cat. No. 2200) for treating Alzjeimer’s Disease (AD) by decreasing Aβ and P-tau formation.
-
CAS Number348086-71-5
-
Structure AvailableY
-
Salt FormNo
-
Molecular FormulaC₁₈H₁₈N₄O₃S₂
-
Molecular Weight402.49
-
Cell PermeableYes
-
Purity≥95% by HPLC
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA potent helicase primase inhibitor
-
Storage Condition-20°C
-
Shipping ConditionGel pack
-
Shelf Life24 months
-
PubChem CID491941
-
SMILESCC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N
-
InChiInChI=1S/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25)
-
InChi KeyIVZKZONQVYTCKC-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Gene symbolIGHV3-57, IGLV6-57, RNU6-57P, MIR1293, CNPPD1, FBXO9, C10orf99, OR5B1P
-
Short nameBAY 57-1293
-
Alternative nameBAY 57-1293
-
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable 3-57 (pseudogene)
-
Synonyms gene name
- immunoglobulin heavy variable 3-57
- immunoglobulin heavy variable 3-57 pseudogene
-
GenBank acession
-
Locus
-
Discovery year2000-04-04
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin lambda variable 6-57
-
GenBank acession
-
Locus
-
Discovery year2000-05-08
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin lambda locus at 22q11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameRNA, U6 small nuclear 57, pseudogene
-
Synonyms gene
-
Synonyms gene name
- RNA, U6 small nuclear 57
-
Locus
-
Discovery year2011-08-08
-
Entrez gene record
-
RefSeq identity
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1293
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNAs
Gene info
-
Identity
-
Gene
-
Long gene namecyclin Pas1/PHO80 domain containing 1
-
Synonyms gene
-
Synonyms gene name
- chromosome 2 open reading frame 24
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2004-04-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameF-box protein 9
-
Synonyms gene name
- F-box only protein 9
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-09-27
-
Entrez gene record
-
Pubmed identfication
-
Classification
- F-boxes other
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namechromosome 10 open reading frame 99
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2004-04-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameolfactory receptor family 5 subfamily B member 1 pseudogene
-
Synonyms gene
-
Synonyms gene name
- olfactory receptor, family 5, subfamily B, member 1 pseudogene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-11-25
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Olfactory receptors, family 5
-
VEGA ID