mAb rat anti-mouse IL-2 Biotin-labeled

Product type

Antibodies to mouse proteins
Notes

clone JES6-5H4
Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. FITC labelling for flow cytometry of antibodies and peptides.
Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus, Rattus norvegicus
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Gene target

mAb IL-2
Gene symbol

IL2, IL36G, IL25, IL22, IL18, IL37, IL1RAPL2, IL6R, IL17C, IL17D
Short name

mAb anti-mouse IL-2 -
Technique

anti-, Mouse, anti, antibody to, antibodies, mouses
Host

Rat
Label

Biotin
Species

Mouse, Mouses, Rats
Alternative name

monoclonal rat Antibody tomouse Interleukin-2 biotinilated-labeled
Alternative technique

murine, antibodies

Identity

HGNC:5997
Gene

IL1RAPL2
Long gene name

interleukin 1 receptor accessory protein like 2
Synonyms
- IL-1R9
- TIGIRR-1
- IL1RAPL-2
- IL1R9
GenBank acession
- AF181285
Locus

Xq22.3
Discovery year

1999-11-19
Entrez gene record

26280
Pubmed identfication
- 10757639
RefSeq identity
- NM_017416
Classification
- TIR domain containing
- Immunoglobulin like domain containing
- Interleukin receptors
VEGA ID

OTTHUMG00000022141
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Name

Drug Labeling
Concept

Scope note: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
Tree numbers
- E05.916.310
Qualifiers

trends, ethics, history, classification, economics, instrumentation, methods, standards, legislation & jurisprudence, statistics & numerical data