Phospho-Leptin Receptor (Tyr1141) Antibody

  • Catalog number
    AF8224
  • Price
    Please ask
  • Size
    100µL
  • Type
    primary antibody
  • Shipping
    Ice bag
  • Antigen
    Phospho-Leptin Receptor (Tyr1141)
  • Reactivity
    Human,Mouse
  • Clonality
    Polyclonal
  • Application
    WB,ELISA
  • Application_advice
    WB 1:1000-3000
  • Epitope
    Phospho Tyr1141
  • Immunogen
    A synthesized peptide derived from human Leptin Receptor (Phospho-Tyr1141).
  • Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
  • Format
    Liquid
  • Concentration
    1mg/ml
  • Fragment
    Fab fragment
  • Storage_Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
  • Specificity
    Leptin Receptor (Phospho-Tyr1141) Antibody detects endogenous levels of Leptin Receptor only when phosphorylated at Tyr1141.
  • GendID
    3953
  • Gene
    LEPR
  • GeneAlias
    LEPR DB OBR
  • Unigene
    Hs.23581;Hs.723178;
  • Swiss Prot
    P48357
  • Weight
    96kDa
  • Properties
    If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Additional gene
    Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • French translation
    anticorps
  • Gene target
  • Short name
    Phospho-Leptin Receptor (Tyr1141) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    phosphorilated-Leptin Receptor (Tyr1141) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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