Phospho-Leptin Receptor (Tyr1141) Antibody
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Catalog number
AF8224
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Price
Please ask
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Size
100µL
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Type
primary antibody
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Shipping
Ice bag
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Antigen
Phospho-Leptin Receptor (Tyr1141)
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Reactivity
Human,Mouse
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Clonality
Polyclonal
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Application
WB,ELISA
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Application_advice
WB 1:1000-3000
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Epitope
Phospho Tyr1141
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Immunogen
A synthesized peptide derived from human Leptin Receptor (Phospho-Tyr1141).
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Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Format
Liquid
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Concentration
1mg/ml
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Fragment
Fab fragment
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Storage_Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
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Specificity
Leptin Receptor (Phospho-Tyr1141) Antibody detects endogenous levels of Leptin Receptor only when phosphorylated at Tyr1141.
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GendID
3953
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Gene
LEPR
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GeneAlias
LEPR DB OBR
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Unigene
Hs.23581;Hs.723178;
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Swiss Prot
P48357
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Weight
96kDa
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Properties
If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
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Gene target
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Short name
Phospho-Leptin Receptor (Tyr1141) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit
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Isotype
IgG
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Alternative name
phosphorilated-Leptin Receptor (Tyr1141) (antibody to-)
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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