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IL-4 murine recombinant

IL-4 murine recombinant is available 3 times from Biovision labs

4138-50 | IL-4, murine recombinant size: 50 ug | 837.50 USD

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4138-10 | IL-4, murine recombinant size: 10 ug | 284.89 USD

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4138-1000 | IL-4, murine recombinant size: 1 mg | 4,012.03 USD

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Synonyms BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,
Alternative_names BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,
Description A key regulator in humoral and adaptive immunity
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Purity ≥98%
Biological activity The ED₅₀ determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is 5 x 10⁵ units/mg.
Molecular Weight 13.5 kDa
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Lyophilized with no additives.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Background Information IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetIL-4 murine
Short name IL-4, murine recombinant
Technique Recombinant
Alternative name Interleukin-4, murine recombinant
Alternative technique rec
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