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Long name
Endothelin A Receptor, aa410-422 (ET-A, ET1-Specific Type Endothelin Receptor, Ednra, ETA, ETRA)
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Antigen
Endothelin A Receptor, aa410-422
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Synonim names
Anti -Endothelin A Receptor, aa410-422 (ET-A, ET1-Specific Type Endothelin Receptor, Ednra, ETA, ETRA)
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Other names
endothelin A receptor, partial; Endothelin-1 receptor; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor; endothelin receptor type A; Endothelin A receptor
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Gene name
Endothelin A Receptor, aa410-422
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Gene synonims
EDNRA; EDNRA; ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR; ETA; ETRA; ET-A; ETA-R; hET-AR
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Category
Antibodies
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Clonality
Polyclonal Antibodies
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Clone
Not applicable to Polyclonal Antibodies
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Reacts with
Human (Homo sapiens), Mouse (Mus musculus), Sheep
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Specificity
This antibody recognizes epitopes on the cytoplasmic side of the receptor and will not block the binding of endothelins. Therefore, the cell membrane must be permeable to the antibody. Species Crossreactivity: Crossreacts with Human, Mouse and Sheep. ;This is an antibody designed to detect Endothelin A Receptor, aa410-422
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Purification method
SerumSerum
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Form Appearance
Supplied as a liquid in PBS, pH 7.2.
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Concentration
Enquire us for detailed information on the concentration of this antibody
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Storage shipping and handling
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. The antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial. Further dilutions can be made in assay buffer.
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Applications
Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
