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Alternative name1
Anti-SHEEP ANTI RAT ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Alternative name2
Ovine ANTI RAT ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Alternative name3
Ovinae ANTI Rattus norvegicus ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Alternative name4
ENDOTHELIN B RECEPTOR
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Alternative name5
N/A
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Other names
endothelin B receptor; Endothelin B receptor; endothelin B receptor; ET-B; ET-BR; endothelin-B receptor; endothelin receptor non-selective type; endothelin receptor type B; Endothelin receptor non-selective type
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
Ednrb; Ednrb; Etb; Ednra; ET-B; ET-BR
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Sheep
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Species reactivity
Rat
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Specificity and cross reactivity
ENDOTHELIN B RECEPTOR This item specifically recognises an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. This item recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. This item does not block the binding of endothelins. This item is reported as suitable for use in immunocytochemistry on acetone fixed cells.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 1.41 miligram per 1 mililiter
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Storage and shipping
Store at +Store productone at +4 degrees Celsius.. DO NOT FREEZE. productone should be stored undiluted. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested for
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology - Paraffin (IHC)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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French translation
anticorps
