SHEEP ANTI RAT ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Catalog number
MBS223880
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Price
Please ask
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Size
0.1 mg
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Products_type
Antibody
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Products_short_name
[ENDOTHELIN B RECEPTOR]
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Other_names
[endothelin B receptor; Endothelin B receptor; endothelin B receptor; ET-B; ET-BR; endothelin receptor non-selective type; endothelin-B receptor; endothelin receptor type B; Endothelin receptor non-selective type]
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Other_gene_names
[Ednrb; Ednrb; Etb; Ednra; ET-B; ET-BR]
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Clonality
Polyclonal
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Reactivity
Human, Mouse
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Specificity
This item specifically recognises an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. This item recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. This item does not block the binding of endothelins. This item is reported as suitable for use in immunocytochemistry on acetone fixed cells.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 1.41mg/ml
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Storage_stability
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology Paraffin
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Gene target
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Gene symbol
GPR37, EDNRB
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Short name
ANTI ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Technique
anti, antibody to
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Host
Sheep
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Isotype
IgG
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Species
Rat, Rats, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
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Alternative name
ovine antibody to RAT ENDOTHELIN B RECEPTOR (C-TERMINAL)
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Alternative technique
antibodies
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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