Celastrol

  • Catalog number
    C249500
  • Price
    Please ask
  • Size
    5 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    In Stock
  • Cas number
    34157-83-0
  • Chemical s molecular weight
    450.61
  • Chemical s main applications
    An antioxidant natural product which inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies. Celastrol also has been shown to have the power to kill tumor cells and can work as an anticarcinogen. Celastrol is also a leptin sensitizer with the potential to reduce weight in obesity (see W499200).
  • Chemical s category
    Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
  • Other name
    3-Hydroxy-2-oxo-24-nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic Acid; Tripterin; Tripterine (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid;
  • Chemical s formula
    C29H38O4
  • Physical properties
    Orange Red Solid
  • Melting temperature
    187-189°C
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    DMSO, Chloroform, Methanol
  • Stability conditions
    No Data Available
  • Storage
    -20°C Freezer
  • Gene target
  • Short name
    Celastrol
  • Alternative name
    Celastrol
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