STO 609,CAMKK kinase inhibitor

Research Area s

Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
Category

Small Molecules
Product Type

Inhibitor
CAS No

52029-86-4
MolecularFormula

C21H14N2O5
Molecular Weight

374.3
Purity

≥98% (TLC)
Solubility

Soluble in DMSO (10 mg/ml)
Appearance

Yellow solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:14234
Gene

NSD1
Long gene name

nuclear receptor binding SET domain protein 1
Synonyms gene
- STO
Synonyms gene name
- Sotos syndrome
Synonyms
- ARA267
- FLJ22263
- KMT3B
GenBank acession
- AK026066
Locus

5q35.3
Discovery year

2002-02-25
Entrez gene record

64324
Pubmed identfication
- 9628876
- 11896389
RefSeq identity
- NM_172349
Classification
- PHD finger proteins
- Lysine methyltransferases
- PWWP domain containing
VEGA ID

OTTHUMG00000130846
Locus Specific Databases
- Global Variome shared LOVD
- LRG_512