gentaur logogentaur logo
x

STO 609, CAMKK kinase inhibitor

  • Catalog number
    SIH-479-25MG
  • Product name
    STO 609, CAMKK kinase inhibitor
  • Size
    25 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    52029-86-4
  • Description
    CAMKK kinase inhibitor
  • Molecular weight
    374,3 g/mol
  • Primary research fields
    Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors
  • Other name
    7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, acetate salt
  • Product category
    Small Molecules
  • Product type
    Inhibitor
  • Chemical formula
    C21H14N2O5
  • Origin
    Synthetic
  • Purity pourcentage
    ≥98% (TLC)
  • Soluble in
    Soluble in DMSO (10 mg/ml)
  • Physical appearance
    Yellow solid
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
  • PubChem number
    16760660
  • Scientific context
    STO 609 is a potent, competitive and selective inhibitor of Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK). STO 609 has been shown to bind to the CaMKK catalytic domain, consequently inhibiting autophosphorylation. It is a valuable tool for exploring the role of the CaM-KK pathway in various physiological processes. STO 609 is cell-permeable.
  • Bibliography
    1. Tokumitsu, H., et al. (2002) J. Biol. Chem. 277(18): 15813–15818. 2. Levine Y.C., Li G.K., & Michel T. (2007) J. Biol. Chem. 282(28): 20351–20364. 3. Anderson K.A., et al. (2008) Cell Metabolism. 7(5): 377–388.
  • Release date
    1-Oct-2014
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure link
    Representative_figure_link
  • Representative figure legend
    Chemical structure of STO 609 (SIH-479), a CAMKK kinase inhibitor. CAS #: 52029-86-4. Molecular Formula: C21H14N2O5. Molecular Weight: 374.3 g/mol. Chemical structure of STO 609, a CAMKK kinase inhibitor (SIH-479). CAS # 52029-86-4. Molecular Formula: C21H14N2O5.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.025
  • Other related products
    Other_related_products
  • Gene target
    STO 609 CAMKK kinase inhibitor
    • Gene info
    Gene info
    Locus Specific Databases:Global Variome shared LOVDLRG_512
  • Gene symbol
    CAMKK2, NSD1
  • Short name
    STO 609, CAMKK kinase inhibitor