Okadaic acid,PP1 and PP2A inhibitor

• Catalog number
  SIH-521-2X20UG
• Price
  Please ask
• Size
  2X20 µg

• Research Area s
  Cell Signaling
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  78111-17-8
• MolecularFormula
  C44H68O13
• Molecular Weight
  805
• Purity
  ≥98% (HPLC)
• Solubility
  Soluble in chloroform, ethanol, methanol, acetone or ethyl acetate
• Appearance
  White crystalline solid
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Okadaic   acid   PP1   PP2A   inhibitor  
• Gene symbol
  PPP2R1B, NPY4R, PPP2R1A, PPA1
• Short name
  Okadaic acid PP1 PP2A inhibitor
• Alternative name
  Okadaic acid,PP1 and PP2A suppressor

Gene info

• Identity
  HGNC:9303
• Gene
  PPP2R1B
• Long gene name
  protein phosphatase 2 scaffold subunit Abeta
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
  • protein phosphatase 2 regulatory subunit A, beta
• Synonyms
  • PR65B
  • PP2A-Abeta
• Synonyms name
  • PP2A-A-beta
  • protein phosphatase 2A, regulatory subunit A, beta isoform
• GenBank acession
  • AF087438
• Locus
  11q23.1
• Discovery year
  1993-01-25
• Entrez gene record
  5519
• Pubmed identfication
  • 2159327
  • 9795170
• RefSeq identity
  • NM_002716
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000166741

Gene info

• Identity
  HGNC:9329
• Gene
  NPY4R
• Long gene name
  neuropeptide Y receptor Y4
• Synonyms gene
  • PPYR1
• Synonyms gene name
  • pancreatic polypeptide receptor 1
• Synonyms
  • Y4
  • PP1
• Locus
  10q11.22
• Discovery year
  1996-04-12
• Entrez gene record
  5540
• Pubmed identfication
  • 9417917
• RefSeq identity
  • NM_005972
• Classification
  • Neuropeptide Y receptors
• VEGA ID
  OTTHUMG00000018108

Gene info

• Identity
  HGNC:9302
• Gene
  PPP2R1A
• Long gene name
  protein phosphatase 2 scaffold subunit Aalpha
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
• Synonyms
  • PR65A
  • PP2A-Aalpha
  • PP2AA
• Synonyms name
  • protein phosphatase 2A, regulatory subunit A, alpha isoform
  • protein phosphatase 2, 65kDa regulatory subunit A
  • protein phosphatase 2A structural subunit A, alpha isoform
• Locus
  19q13.41
• Discovery year
  1993-01-25
• Entrez gene record
  5518
• RefSeq identity
  • NM_014225
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000137367

Gene info

• Identity
  HGNC:9226
• Gene
  PPA1
• Long gene name
  inorganic pyrophosphatase 1
• Synonyms gene
  • PP
• Synonyms gene name
  • pyrophosphatase (inorganic)
  • pyrophosphatase (inorganic) 1
• Synonyms
  • SID6-8061
  • Ppase
  • IOPPP
  • PP1
• Synonyms name
  • cytosolic inorganic pyrophosphatase
  • inorganic pyrophosphatase 1
  • pyrophosphate phospho-hydrolase
  • inorganic diphosphatase 1
• GenBank acession
  • AF154065
• Locus
  10q22.1
• Discovery year
  2001-06-22
• Entrez gene record
  5464
• Pubmed identfication
  • 10542310
  • 975879
• RefSeq identity
  • NM_021129
• VEGA ID
  OTTHUMG00000018399

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