NPC 15437,PKC kinase inhibitor

Research Area s

Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
Category

Small Molecules
Product Type

Inhibitor
CAS No

141774-20-1
MolecularFormula

C25H52Cl2N4O2
Molecular Weight

511.6
Purity

≥98% (HPLC)
Solubility

Soluble in water, DMSO or methanol
Appearance

White to off-white solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:30500
Gene

PRRT2
Long gene name

proline rich transmembrane protein 2
Synonyms gene
- ICCA
- DYT10
Synonyms gene name
- infantile convulsions and paroxysmal choreoathetosis
- dystonia 10
- proline-rich transmembrane protein 2
Synonyms
- FLJ25513
- DKFZp547J199
- IFITMD1
- FICCA
- DSPB3
- PKC
- EKD1
Synonyms name
- interferon induced transmembrane protein domain containing 1
- dispanin subfamily B member 3
GenBank acession
- BC011405
Locus

16p11.2
Discovery year

2005-11-25
Entrez gene record

112476
Pubmed identfication
RefSeq identity
- NM_145239
Classification
- interferon induced transmembrane protein domain containing
VEGA ID

OTTHUMG00000177142