IKK alpha + IKK beta Antibody (pSer176/177): HRP

• Catalog number
  SPC-1390D-HRP
• Price
  Please ask
• Size
  100 µl

• Target
  IKK alpha + IKK beta (pSer176/177)
• Conjugate
  HRP
• Research Area s
  Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, Cell Signaling, Epigenetics and Nuclear Signaling, Nuclear Signaling Pathways, NFkB Pathway, IKK, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Inflammatory Mediators, Immunology, Innate Immunity, TLR Signaling
• Alternative Name s
  IKKA Antibody, IKKB Antibody, CHUK Antibody, IKKα/β Antibody, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor Antibody, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit Antibody, I Kappa B Kinase 1 Antibody, TCF16 Antibody, Conserved Helix Loop Helix Ubiquitous Kinase Antibody, IKK A Antibody, IkappaB kinase Antibody, IKKA_HUMAN Antibody, IKK1 Antibody, chuk Antibody, Inhibitor of nuclear factor kappa-B kinase subunit alpha Antibody, IKK-A Antibody, IKK-alpha Antibody, CHUK1 Antibody, Conserved helix loop ubiquitous kinase Antibody, Nuclear factor NF kappa B inhibitor kinase alpha Antibody, IKK 1 Antibody, I-kappa-B kinase alpha Antibody, IkBKA Antibody, Conserved helix-loop-helix ubiquitous kinase Antibody, Nuclear factor NF-kappa-B inhibitor kinase alpha Antibody, TCF-16 Antibody, Nuclear Factor Kappa B Inhibitor Kinase Alpha Antibody, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells Antibody, Nuclear factor NFkappaB inhibitor kinase alpha Antibody, I-kappa-B kinase 1 Antibody, NFKBIKA Antibody, IKK a kinase Antibody, IkB kinase alpha subunit Antibody, I Kappa B Kinase Alpha Antibody, Transcription factor 16 Antibody, EC:2.7.11.10 Antibody, NFKBIKB Antibody, Inhibitor of nuclear factor kappa-B kinase subunit beta Antibody, I kappa B kinase beta Antibody, Nuclear factor NF-kappa-B inhibitor kinase beta Antibody, IKKB Antibody, IKKB_HUMAN Antibody, I-kappa-B kinase 2 Antibody, IKK-beta Antibody, IKBKB Antibody, IKK2 Antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta Antibody, IKK beta Antibody, I-kappa-B-kinase beta Antibody, IKK-B Antibody, I kappa B kinase 2 Antibody, IMD15 Antibody
• Category
  Antibodies
• Product Type
  Polyclonal
• Immunogen
  Synthetic phospho-peptide from human IKK alpha + IKK beta proteins around the phosphorylation sites of IKKα at serine 176 (pSer176) and IKKβ at serine 177 (pSer177).
• Immunogen Species
  Human
• Accession Number
  NP_001269.3/NP_001177649.1
• Gene ID
  1147/3551
• Swiss Prot
  O15111/O14920
• Applications
  WB, IHC, ELISA
• Host Species
  Rabbit
• Species Reactivity
  Human, Mouse, Rat
• Antibody Dilution
  WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user.
• Purification
  Peptide Affinity Purified
• Storage Buffer
  PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
• Specificity
  Detects endogenous levels of IKKα only when phosphorylated at serine 176 (pSer176) and IKKβ only when phosphorylated at serine 177 (pSer177). Detects a band at ~80 kDa.
• Storage Temperature
  -20ºC
• Shipping Temperature
  Blue Ice or 4ºC
• Cellular Localization
  Nucleus, Cytoplasm, Cytosol, Ikappab Kinase Complex, Nucleoplasm, Plasma Membrane, Cd40 Receptor Complex, Cytoplasmic Side Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane Raft
• Field of Use
  For in vitro research use only.
• Technical data
• SDS
• Gross Weight kg
  1.4
• Net Weight g
  0.1
• Description
  The IKK alpha + IKK beta Antibody (pSer176/177): is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by StressMarq they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  IKK   alpha   IKK   beta   pSer176/177  
• Gene symbol
  IKBKE, IKBKB, CHUK, IKBKG
• Short name
  IKK alpha + IKK beta Antibody (pSer176/177):
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Label
  HRP
• Alternative name
  IKK a + IKK b (antibody to-) (pSer176/177): horseradish peroxidase
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14552
• Gene
  IKBKE
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit epsilon
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
• Synonyms
  • IKKE
  • IKK-i
  • KIAA0151
• GenBank acession
  • AB016590
• Locus
  1q32.1
• Discovery year
  2002-12-02
• Entrez gene record
  9641
• Pubmed identfication
  • 10421793
  • 10882136
• Classification
  • I kappa B kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000184613

Gene info

• Identity
  HGNC:5960
• Gene
  IKBKB
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit beta
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• Synonyms
  • IKK2
  • NFKBIKB
  • IKK-beta
  • IKKB
• GenBank acession
  • AF029684
• Locus
  8p11.21
• Discovery year
  1998-02-11
• Entrez gene record
  3551
• Pubmed identfication
  • 9878263
  • 9763654
  • 18308615
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000164092
• Locus Specific Databases
  • LRG_1241

Gene info

• Identity
  HGNC:1974
• Gene
  CHUK
• Long gene name
  component of inhibitor of nuclear factor kappa B kinase complex
• Synonyms gene
  • TCF16
• Synonyms gene name
  • conserved helix-loop-helix ubiquitous kinase
• Synonyms
  • IKK1
  • IKK-alpha
  • IkBKA
  • NFKBIKA
  • IKKA
• Synonyms name
  • inhibitor of nuclear factor kappa-B kinase subunit alpha
  • I-kappa-B kinase
• GenBank acession
  • AF009225
• Locus
  10q24.31
• Discovery year
  1995-03-15
• Entrez gene record
  1147
• Pubmed identfication
  • 7558004
  • 16902410
• RefSeq identity
  • NM_001278
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000018899

Gene info

• Identity
  HGNC:5961
• Gene
  IKBKG
• Long gene name
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
• Synonyms gene
  • IP2
  • IP1
• Synonyms gene name
  • incontinentia pigmenti
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • inhibitor of nuclear factor kappa B kinase subunit gamma
• Synonyms
  • IKK-gamma
  • NEMO
  • Fip3p
  • FIP-3
  • FIP3
  • ZC2HC9
  • IKKAP1
  • IKKG
• Synonyms name
  • NF-kappa-B essential modulator
  • IkB kinase-associated protein 1
  • I-kappa-B kinase subunit gamma
  • IkB kinase subunit gamma
  • 14.7K (adenovirus E3 protein) interacting protein 3
• GenBank acession
  • AF074382
• Locus
  Xq28
• Discovery year
  1998-09-30
• Entrez gene record
  8517
• Pubmed identfication
  • 9751060
  • 10087442
  • 11590134
  • 11242109
• RefSeq identity
  • NM_003639
• Classification
  • Zinc fingers C2HC-type
  • IKK complex
• VEGA ID
  OTTHUMG00000024234
• Locus Specific Databases
  • IKBKGbase: Mutation registry for Nemo deficiency
  • Global Variome shared LOVD
  • LRG_70

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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