IKK alpha + IKK beta Antibody (pSer176/177): PerCP

• Catalog number
  SPC-1390D-PCP
• Price
  Please ask
• Size
  100 µl

• Target
  IKK alpha + IKK beta (pSer176/177)
• Conjugate
  PerCP
• Research Area s
  Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, Cell Signaling, Epigenetics and Nuclear Signaling, Nuclear Signaling Pathways, NFkB Pathway, IKK, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Inflammatory Mediators, Immunology, Innate Immunity, TLR Signaling
• Alternative Name s
  IKKA Antibody, IKKB Antibody, CHUK Antibody, IKKα/β Antibody, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor Antibody, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit Antibody, I Kappa B Kinase 1 Antibody, TCF16 Antibody, Conserved Helix Loop Helix Ubiquitous Kinase Antibody, IKK A Antibody, IkappaB kinase Antibody, IKKA_HUMAN Antibody, IKK1 Antibody, chuk Antibody, Inhibitor of nuclear factor kappa-B kinase subunit alpha Antibody, IKK-A Antibody, IKK-alpha Antibody, CHUK1 Antibody, Conserved helix loop ubiquitous kinase Antibody, Nuclear factor NF kappa B inhibitor kinase alpha Antibody, IKK 1 Antibody, I-kappa-B kinase alpha Antibody, IkBKA Antibody, Conserved helix-loop-helix ubiquitous kinase Antibody, Nuclear factor NF-kappa-B inhibitor kinase alpha Antibody, TCF-16 Antibody, Nuclear Factor Kappa B Inhibitor Kinase Alpha Antibody, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells Antibody, Nuclear factor NFkappaB inhibitor kinase alpha Antibody, I-kappa-B kinase 1 Antibody, NFKBIKA Antibody, IKK a kinase Antibody, IkB kinase alpha subunit Antibody, I Kappa B Kinase Alpha Antibody, Transcription factor 16 Antibody, EC:2.7.11.10 Antibody, NFKBIKB Antibody, Inhibitor of nuclear factor kappa-B kinase subunit beta Antibody, I kappa B kinase beta Antibody, Nuclear factor NF-kappa-B inhibitor kinase beta Antibody, IKKB Antibody, IKKB_HUMAN Antibody, I-kappa-B kinase 2 Antibody, IKK-beta Antibody, IKBKB Antibody, IKK2 Antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta Antibody, IKK beta Antibody, I-kappa-B-kinase beta Antibody, IKK-B Antibody, I kappa B kinase 2 Antibody, IMD15 Antibody
• Category
  Antibodies
• Product Type
  Polyclonal
• Immunogen
  Synthetic phospho-peptide from human IKK alpha + IKK beta proteins around the phosphorylation sites of IKKα at serine 176 (pSer176) and IKKβ at serine 177 (pSer177).
• Immunogen Species
  Human
• Accession Number
  NP_001269.3/NP_001177649.1
• Gene ID
  1147/3551
• Swiss Prot
  O15111/O14920
• Applications
  WB, IHC, ELISA
• Host Species
  Rabbit
• Species Reactivity
  Human, Mouse, Rat
• Antibody Dilution
  WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user.
• Purification
  Peptide Affinity Purified
• Storage Buffer
  PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
• Specificity
  Detects endogenous levels of IKKα only when phosphorylated at serine 176 (pSer176) and IKKβ only when phosphorylated at serine 177 (pSer177). Detects a band at ~80 kDa.
• Storage Temperature
  -20ºC
• Shipping Temperature
  Blue Ice or 4ºC
• Cellular Localization
  Nucleus, Cytoplasm, Cytosol, Ikappab Kinase Complex, Nucleoplasm, Plasma Membrane, Cd40 Receptor Complex, Cytoplasmic Side Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane Raft
• Field of Use
  For in vitro research use only.
• Technical data
• SDS
• Gross Weight kg
  1.4
• Net Weight g
  0.1
• Description
  The IKK alpha + IKK beta Antibody (pSer176/177): PerCP is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by StressMarq they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional conjugate
  Peridinin chlorophyll (PerCP)
• French translation
  anticorps

• Gene target
  IKK   alpha   IKK   beta   pSer176/177  
• Gene symbol
  IKBKE, IKBKB, CHUK, IKBKG
• Short name
  IKK alpha + IKK beta Antibody (pSer176/177): PerCP
• Technique
  Antibody, Percp, antibodies against human proteins, antibodies for, Peridinin chlorophyll protein (PerCP) has a 677 nanometer maximum emission, red, when excited at 488 nanometers and the IKK alpha + IKK beta Antibody (pSer176/177): PerCP is detected on the FL3 detector of a FACSCalibur or FACScan. A PerCP dye is also available (PerCP-Cy5.5, also written Cy5.5-PerCP). PerCP is not suited for the high-powered lasing (>150mW) applications, such as on a MoFlo, due to it photobleaching (features/ qualities/ traits). PerCP conjugates can only be received/be gotten from the Becton Dickinson/Pharmingen group of companies or from StressMarq.
• Label
  PerCP
• Alternative name
  IKK a + IKK b (antibody to-) (pSer176/177): PerCP
• Alternative technique
  antibodies, antibodies-percp

Gene info

• Identity
  HGNC:14552
• Gene
  IKBKE
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit epsilon
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
• Synonyms
  • IKKE
  • IKK-i
  • KIAA0151
• GenBank acession
  • AB016590
• Locus
  1q32.1
• Discovery year
  2002-12-02
• Entrez gene record
  9641
• Pubmed identfication
  • 10421793
  • 10882136
• Classification
  • I kappa B kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000184613

Gene info

• Identity
  HGNC:5960
• Gene
  IKBKB
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit beta
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• Synonyms
  • IKK2
  • NFKBIKB
  • IKK-beta
  • IKKB
• GenBank acession
  • AF029684
• Locus
  8p11.21
• Discovery year
  1998-02-11
• Entrez gene record
  3551
• Pubmed identfication
  • 9878263
  • 9763654
  • 18308615
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000164092
• Locus Specific Databases
  • LRG_1241

Gene info

• Identity
  HGNC:1974
• Gene
  CHUK
• Long gene name
  component of inhibitor of nuclear factor kappa B kinase complex
• Synonyms gene
  • TCF16
• Synonyms gene name
  • conserved helix-loop-helix ubiquitous kinase
• Synonyms
  • IKK1
  • IKK-alpha
  • IkBKA
  • NFKBIKA
  • IKKA
• Synonyms name
  • inhibitor of nuclear factor kappa-B kinase subunit alpha
  • I-kappa-B kinase
• GenBank acession
  • AF009225
• Locus
  10q24.31
• Discovery year
  1995-03-15
• Entrez gene record
  1147
• Pubmed identfication
  • 7558004
  • 16902410
• RefSeq identity
  • NM_001278
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000018899

Gene info

• Identity
  HGNC:5961
• Gene
  IKBKG
• Long gene name
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
• Synonyms gene
  • IP2
  • IP1
• Synonyms gene name
  • incontinentia pigmenti
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • inhibitor of nuclear factor kappa B kinase subunit gamma
• Synonyms
  • IKK-gamma
  • NEMO
  • Fip3p
  • FIP-3
  • FIP3
  • ZC2HC9
  • IKKAP1
  • IKKG
• Synonyms name
  • NF-kappa-B essential modulator
  • IkB kinase-associated protein 1
  • I-kappa-B kinase subunit gamma
  • IkB kinase subunit gamma
  • 14.7K (adenovirus E3 protein) interacting protein 3
• GenBank acession
  • AF074382
• Locus
  Xq28
• Discovery year
  1998-09-30
• Entrez gene record
  8517
• Pubmed identfication
  • 9751060
  • 10087442
  • 11590134
  • 11242109
• RefSeq identity
  • NM_003639
• Classification
  • Zinc fingers C2HC-type
  • IKK complex
• VEGA ID
  OTTHUMG00000024234
• Locus Specific Databases
  • IKBKGbase: Mutation registry for Nemo deficiency
  • Global Variome shared LOVD
  • LRG_70

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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