FTY720 Hydrochloride,S1P receptor ligand

Research Area s

Cell signaling
Category

Small Molecules
Product Type

Agonist
CAS No

162359-56-0
MolecularFormula

C19H34ClNO2
Molecular Weight

343.9
Purity

>98% (TLC); NMR (Conforms)
Solubility

Soluble to 100 mg/ml in DMSO or to 40 mg/ml in ethanol (warmed)
Appearance

White solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.