FTY720 Hydrochloride

  • Catalog number
    F805000
  • Price
    Please ask
  • Size
    5 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    In Stock
  • Cas number
    162359-56-0
  • Chemical s molecular weight
    343.93
  • Chemical s main applications
    FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
  • Chemical s category
    Aromatics, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Other name
    2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol Hydrochloride; Fingolimod Hydrochloride;
  • Chemical s formula
    C19H34ClNO2
  • Physical properties
    White Solid
  • Melting temperature
    102-107°C
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    DMSO (Slightly), Methanol (Slightly), Water (Slightly)
  • Stability conditions
    No Data Available
  • Storage
    -20°C Freezer
  • Gene target
  • Short name
    FTY720 Hydrochloride
  • Alternative name
    FTY720 Hydrochloride
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