-
Chemical available in other sizes
Please inquire size and price
-
Stock availability
In Stock
-
Cas number
162359-56-0
-
Chemical s molecular weight
343.93
-
Chemical s main applications
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
-
Chemical s category
Aromatics, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
-
Other name
2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol Hydrochloride; Fingolimod Hydrochloride;
-
Chemical s formula
C19H34ClNO2
-
Physical properties
White Solid
-
Melting temperature
102-107°C
-
Boiling temperature
No Data Available
-
Chemical s soluble in
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
-
Stability conditions
No Data Available
-
Storage
-20°C Freezer
-