AAL 993,VEGFR inhibitor
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Catalog numberSIH-424-5MG
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PricePlease ask
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Size5 mg
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Research Area sCell Signaling , Cancer , Apoptosis , Cardiovascular System , Cancer Growth Inhibitors , Growth Factor Receptor Inhibitors
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CategorySmall Molecules
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Product TypeInhibitor
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CAS No269390-77-4
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MolecularFormulaC20H16F3N3O
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Molecular Weight371.4
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Purity≥98% (TLC)
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SolubilitySoluble in DMSO (>25 mg/ml) or ethanol (15 mg/ml)
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AppearancePale yellow solid
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Storage Temperature-20°C
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Shipping TemperatureShipped Ambient
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolFLT4, KDR
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Short nameAAL 993 VEGFR inhibitor
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Alternative nameAAL 993,VEGFR suppressor
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Gene info
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Identity
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Gene
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Long gene namefms related receptor tyrosine kinase 4
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Synonyms gene name
- fms-related tyrosine kinase 4
- fms related tyrosine kinase 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-10-25
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Entrez gene record
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Pubmed identfication
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Classification
- I-set domain containing
- Receptor tyrosine kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekinase insert domain receptor
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Synonyms gene name
- kinase insert domain receptor (a type III receptor tyrosine kinase)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-07-10
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Entrez gene record
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Pubmed identfication
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Classification
- Receptor tyrosine kinases
- CD molecules
- I-set domain containing
- V-set domain containing
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VEGA ID
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Locus Specific Databases