- Catalog numberR30470
- Product nameVEGFR Antibody
- Size0.1mg
- PriceAsk For Price
- Short nameAnti-VEGFR
- CategoryAntibody
- Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
- FormAntigen affinity purified
- ConjugationUnconjugated
- ClonePolyclonal antibody
- Recognised antigenVEGFR
- Host animalRabbit (Oryctolagus cuniculus)
- ClonalityPolyclonal (rabbit origin)
- IsotypeRabbit IgG
- Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
- Tested applicationsWB
- Recommended dilutionsWestern blot: 0.5-1ug/ml
- NotesThe stated application concentrations are suggested starting amounts. Titration of the VEGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
- Intented useThis VEGFR antibodyis to be used only for research purposes and not for diagnostics..
- UniprotP17948
- PurityAntigen affinity
- DescriptionVascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene and belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
- ImmunogenAn amino acid sequence from the C-terminus of human VEGF Receptor 1 (HVSEGKRRFTYDHAELERK) was used as the immunogen for this VEGFR antibody.
- StorageAfter reconstitution, the VEGFR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
- Gene targetVEGFR
- Identity:HGNC:3767
- Gene:FLT4
- Long gene name:fms related receptor tyrosine kinase 4
- Synonyms gene name:fms-related tyrosine kinase 4, fms related tyrosine kinase 4
- Synonyms:VEGFR3, PCLVEGFR-3
- Discovery year:1991-10-25
- Entrez gene record:2324
- Pubmed identification:1319394
- Classification:I-set domain containing, Receptor tyrosine kinases
- VEGA ID:OTTHUMG00000130931
- Identity:HGNC:6307
- Gene:KDR
- Long gene name:kinase insert domain receptor
- Synonyms gene name:kinase insert domain receptor (a type III receptor tyrosine kinase)
- Synonyms:FLK1VEGFRVEGFR2CD309
- Discovery year:1991-07-10
- Entrez gene record:3791
- Pubmed identification:1417831
- Classification:Receptor tyrosine kinases, CD molecules, I-set domain containing, V-set domain containing
- VEGA ID:OTTHUMG00000128734
- Gene symbolFLT4, KDR
- isotype filter
- Rabbit IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Gene info
Locus Specific Databases:The Globin Gene ServerLRG_1198