17-AAG,Hsp90 inhibitor

• Catalog number
  SIH-100-5MG
• Price
  Please ask
• Size
  5 mg

• Research Area s
  Cancer , Heat Shock
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  75747-14-7
• MolecularFormula
  C31H43N3O8
• Molecular Weight
  585.7
• Purity
  >98% (TLC); NMR (conforms)
• Solubility
  Soluble in DMSO (>50 mg/ml) or ethanol (5 mg/ml)
• Appearance
  Red to dark red powder
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  17-AAG   Hsp90   inhibitor  
• Gene symbol
  PIRC95, PIRC91, PIRC90, PIRC93, PIRC92, SNORD115-17, IGHV3OR16-17, SNORD116-17
• Short name
  17-AAG Hsp90 inhibitor
• Alternative name
  17-AAG,Hsp90 suppressor

Gene info

• Identity
  HGNC:37599
• Gene
  PIRC95
• Long gene name
  piwi-interacting RNA cluster 95
• Locus
  17
• Discovery year
  2009-11-05
• Entrez gene record
  100313935
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37595
• Gene
  PIRC91
• Long gene name
  piwi-interacting RNA cluster 91
• Locus
  17
• Discovery year
  2009-11-05
• Entrez gene record
  100313900
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37594
• Gene
  PIRC90
• Long gene name
  piwi-interacting RNA cluster 90
• Locus
  17
• Discovery year
  2009-11-05
• Entrez gene record
  100313798
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37597
• Gene
  PIRC93
• Long gene name
  piwi-interacting RNA cluster 93
• Locus
  17
• Discovery year
  2009-11-05
• Entrez gene record
  100313934
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37596
• Gene
  PIRC92
• Long gene name
  piwi-interacting RNA cluster 92
• Locus
  17
• Discovery year
  2009-11-05
• Entrez gene record
  100313920
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33036
• Gene
  SNORD115-17
• Long gene name
  small nucleolar RNA, C/D box 115-17
• Synonyms
  • HBII-52-17
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033455
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003309.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:55105
• Gene
  IGHV3OR16-17
• Long gene name
  immunoglobulin heavy variable 3/OR16-17 (non-functional)
• Synonyms
  • IGHV3/OR16-17
• Locus
  16p11.2
• Discovery year
  2020-06-26
• Entrez gene record
  390714
• Classification
  • Immunoglobulin heavy (IGH) orphons

Gene info

• Identity
  HGNC:33083
• Gene
  SNORD116-17
• Long gene name
  small nucleolar RNA, C/D box 116-17
• Synonyms
  • HBII-85-17
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033429
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003332
• Classification
  • Small nucleolar RNAs, C/D box

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