Piceatannol, SIRT1 activator

• Catalog number
  SIH-358-5MG
• Price
  Please ask
• Size
  5 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  10083-24-6
• Description
  SIRT1 activator
• Molecular weight
  244,2 g/mol
• Primary research fields
  Cell Signaling, Epigenetics
• Other name
  3,3′,4,5′-Tetrahydroxy-transstilbene; 4-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]-1,2-benzenediol
• Product category
  Small Molecules
• Product type
  Activator
• Chemical formula
  C14H12O4
• Origin
  Synthetic
• Purity pourcentage
  >98% (TLC), NMR conforms
• Soluble in
  Soluble in 10 mg/ml DMSO or 10 mg/ml Ethanol
• Physical appearance
  Light Pink Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Caution- Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
• PubChem number
  667639
• Scientific context
  A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M) (1). Stimulates Sirt1 (2).
• Bibliography
  1. Seow C.J., et al. (2002) Eur. J. Pharmacol. 443: 189. 2. Howitz K.T., et al. (2003) Nature 425: 191.
• Release date
  1-Aug-2012
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of Piceatannol (SIH-358), a SIRT1 activator. CAS #: 10083-24-6. Molecular Formula: C14H12O4 . Molecular Weight: 244.2 g/mol. Chemical structure of Piceatannol, a SIRT1 activator (SIH-358). CAS # 10083-24-6. Molecular Formula: C14H12O4 .
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.005
• Other related products

• Gene target
  Piceatannol   SIRT1   activator  
• Gene symbol
  SIRT1, SIRT1-AS
• Short name
  Piceatannol, SIRT1 activator
• Alternative name
  Piceatannol, sirtuin 1 activator
• Alternative to gene target
  sirtuin 1, SIR2L1, SIRT1 and IDBG-75847 and ENSG00000096717 and 23411, keratin filament binding, nuclei, Sirt1 and IDBG-159441 and ENSMUSG00000020063 and 93759, SIRT1 and IDBG-629119 and ENSBTAG00000014023 and 613629

Gene info

• Identity
  HGNC:14929
• Gene
  SIRT1
• Long gene name
  sirtuin 1
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1
  • sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
• Synonyms
  • SIR2L1
• GenBank acession
  • AF083106
• Locus
  10q21.3
• Discovery year
  2001-03-20
• Entrez gene record
  23411
• Pubmed identfication
  • 10381378
• RefSeq identity
  • NM_012238
• Classification
  • eNoSC complex
  • Sirtuins
• VEGA ID
  OTTHUMG00000018340

Gene info

• Identity
  HGNC:51912
• Gene
  SIRT1-AS
• Long gene name
  SIRT1 antisense RNA
• Locus
  10q21.3
• Discovery year
  2015-09-23
• Entrez gene record
  106633813
• Pubmed identfication
  • 26324025
• Classification
  • Antisense RNAs

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