Piceatannol, SIRT1 activator
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Catalog number
SIH-358-25MG
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Price
Please ask
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Size
25 mg
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Stock availabilitIn Stock
In Stock
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CAS number
10083-24-6
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Description
SIRT1 activator
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Molecular weight
244,2 g/mol
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Primary research fields
Cell Signaling, Epigenetics
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Other name
3,3′,4,5′-Tetrahydroxy-transstilbene; 4-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]-1,2-benzenediol
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Product category
Small Molecules
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Product type
Activator
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Chemical formula
C14H12O4
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Origin
Synthetic
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Purity pourcentage
>98% (TLC), NMR conforms
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Soluble in
Soluble in 10 mg/ml DMSO or 10 mg/ml Ethanol
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Physical appearance
Light Pink Solid
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Storage recommendations
-20ºC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: Caution- Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
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PubChem number
667639
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Scientific context
A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M) (1). Stimulates Sirt1 (2).
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Bibliography
1. Seow C.J., et al. (2002) Eur. J. Pharmacol. 443: 189. 2. Howitz K.T., et al. (2003) Nature 425: 191.
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Release date
1-Aug-2012
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of Piceatannol (SIH-358), a SIRT1 activator. CAS #: 10083-24-6. Molecular Formula: C14H12O4 . Molecular Weight: 244.2 g/mol. Chemical structure of Piceatannol, a SIRT1 activator (SIH-358). CAS # 10083-24-6. Molecular Formula: C14H12O4 .
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.025
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Gene target
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Gene symbol
SIRT1-AS, SIRT1
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Short name
Piceatannol, SIRT1 activator
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Alternative name
Piceatannol, sirtuin 1 activator
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Alternative to gene target
sirtuin 1, SIR2L1, SIRT1 and IDBG-75847 and ENSG00000096717 and 23411, keratin filament binding, nuclei, Sirt1 and IDBG-159441 and ENSMUSG00000020063 and 93759, SIRT1 and IDBG-629119 and ENSBTAG00000014023 and 613629
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Gene info
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Identity
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Gene
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Long gene name
SIRT1 antisense RNA
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Locus
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Discovery year
2015-09-23
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Entrez gene record
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Pubmed identfication
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Classification
Gene info
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Identity
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Gene
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Long gene name
sirtuin 1
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Synonyms gene name
- sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1
- sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-03-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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