BzATP, Prototypic P2X7 receptor agonist
-
Catalog number
SIH-420-25MG
-
Price
Please ask
-
Size
25 mg
-
-
Stock availabilitIn Stock
In Stock
-
CAS number
112898-15-4
-
Description
Prototypic P2X7 receptor agonist
-
Molecular weight
1018,97 g/mol
-
Primary research fields
Neuroscience, Ion Channels
-
Other name
2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
-
Product category
Small Molecules
-
Product type
Agonist
-
Chemical formula
C24H24N5O15P3•C18H45N3
-
Origin
Synthetic
-
Purity pourcentage
97.70%
-
Soluble in
Soluble in water.
-
Physical appearance
Off white solid
-
Storage recommendations
-20ºC
-
Shipping recommendations
Shipped Ambient
-
Safety information
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
-
PubChem number
71308559
-
Scientific context
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP. This small molecule also exhibits partial agonist activity at P2X1 and P2Y1 receptors. Lastly, it can be used as a photoaffinity label for ATPase.
-
Bibliography
1. Young M., Pelegrin P., & Surprenant A. (2007) Mol Pharmacol. 92-100.
-
Release date
21-May-2014
-
PubMed number
Refer to PubMed
-
Tested applications
To be tested
-
Tested reactivity
To be tested
-
-
Representative figure legend
Chemical structure of BzATP (SIH-420), a Prototypic P2X7 receptor agonist. CAS #: 112898-15-4. Molecular Formula: C24H24N5O15P3.C18H45N3. Molecular Weight: 1018.97 g/mol. Chemical structure of BzATP, a Prototypic P2X7 receptor agonist (SIH-420). CAS # 112898-15-4. Molecular Formula: C24H24N5O15P3.C18H45N3.
-
Warning information
Non-hazardous
-
Country of production
Canada
-
Total weight kg
0.25
-
Net weight g
0.025
-
-
Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
P2RX7
-
Short name
BzATP, Prototypic P2X7 receptor agonist
-
Alternative name
BzATP, Prototypic P2X7 receptor agonist
-
Gene info
Similar products
