Orexin 2 Receptor Agonist
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Catalog numberB1124-5
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Price:
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Size5 mg
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Alternative_name4'-methoxy-N,N-dimethyl-3'-(N-(3-((2-(3-methylbenzamido)ethyl)amino)phenyl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
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DescriptionOrexin-2 receptor agonist is a potent and selective selective nonpeptidic orexin2 receptor (OX2R) agonist (OX2R EC₅₀ = 0.023 μM).
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CAS Number1796565-52-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₃₂H₃₄N₄O₅S
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Molecular Weight586.22
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>5 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective nonpeptidic orexin 2 receptor (OX2R) agonist
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID91810287
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SMILESCC1=CC=CC(=C1)C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)C)OC
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InChi1S/C32H34N4O5S/c1-22-8-5-10-25(18-22)31(37)34-17-16-33-27-12-7-13-28(21-27)35-42(39,40)30-20-24(14-15-29(30)41-4)23-9-6-11-26(19-23)32(38)36(2)3/h5-15,18-21,33,35H,16-17H2,1-4H3,(H,34,37)
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InChi KeyRHLMXWCISNJNDH-UHFFFAOYSA-N
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MSDS AvailableYes
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Additional descriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Short nameOrexin 2 Receptor Agonist
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Alternative nameOrexin 2 Receptor Agonist
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