Recombinant human Thyroid hormone receptor beta
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Catalog numberAP70849-1mg
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Price:
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Size1mg
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Similar nameThyroid hormone receptor beta
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Other nameRecombinant Human Thyroid hormone receptor beta Expressed in E.coli
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SynonymRecombinant Thyroid hormone receptor beta
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Little descriptionOur Thyroid hormone receptor beta is a recombinant Human protein expressed in E.coli with His-SUMO-tag
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Expression systemE.coli
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Origin speciesHuman
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ConjugationHis-SUMO-tag
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StorageFor long term storage, keep the Recombinant human Thyroid hormone receptor beta frozen at -20 or -80 degrees Celsius. Working aliquots can be stored at +4C for a few weeks. We recommend cycles of freezing and thawing to be avoided, as they will most certainly denaturate the polypeptide chains of the protein.
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ShippingThe Human Thyroid hormone receptor beta is shipped on ice packs.
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DescriptionHormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTHRB
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Short nameRecombinant Thyroid hormone receptor beta
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. SAB advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameHuman Thyroid hormone receptor beta
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Alternative techniquerec
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Tissuethyroid
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Gene info
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Identity
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Gene
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Long gene namethyroid hormone receptor beta
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Synonyms gene
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Synonyms gene name
- thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
- pituitary resistance to thyroid hormone
- thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
- thyroid hormone receptor, beta
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-08-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Thyroid hormone receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data