anti-TRAF3 Antibody

• Catalog number
  3599
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TRAF3 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are the major signal transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. TRAF3 was first identified by its interaction with CD40 and the Epstein-Barr virus transforming protein LMP1. Several TRAF3 mRNA splice variants exist and some of these can activate the transcription factor NF-kB. Besides CD40, TRAF3 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF2 and the apoptosis inhibitors cIAP1 and Smac. It has been suggested that TRAF3 induces mitochondria-mediated apoptosis upon binding of the TNF family cytokine LIGHT by LTbetaR.
• Gene names
  TRAF3 Antibody: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp, CAP1, TNF receptor-associated factor 3
• Antibodie s label
  unlabelled serum
• Purity
  TRAF3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TRAF3 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human TRAF3.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  TRAF3 antibody can be used for the detection of TRAF3 by Western blot at 1 - 2 ug/mL. For immunofluorescence start at 2 ug/mL.
• Suspention pH azide
  TRAF3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TRAF3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  22027618
• Ncbi nr
  NP_663777
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7187
• GENE symbol
  TRAF3
• Antigene name
  TNF receptor-associated factor 3
• Source
  Homo sapiens
• Protein nr
  Q13114
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRAF3  
• Gene symbol
  TRAF3
• Short name
  anti-TRAF3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTRAF3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  TNF receptor-associated factor 3, CAP-1 and CAP1 and CD40bp and CRAF1 and IIAE5 and LAP1, TRAF3 and IDBG-21240 and ENSG00000131323 and 7187, thioesterase binding, Plasma membranes, Traf3 and IDBG-172558 and ENSMUSG00000021277 and 22031, TRAF3 and IDBG-635183 and ENSBTAG00000013475 and 506182

Gene info

• Identity
  HGNC:12033
• Gene
  TRAF3
• Long gene name
  TNF receptor associated factor 3
• Synonyms
  • CAP-1
  • CD40bp
  • CRAF1
  • LAP1
  • RNF118
• GenBank acession
  • U21092
• Locus
  14q32.32
• Discovery year
  1998-05-05
• Entrez gene record
  7187
• Pubmed identfication
  • 7530216
  • 7859281
• RefSeq identity
  • NM_145725
• Classification
  • Ring finger proteins
  • Zinc fingers
  • TNF receptor associated factors
• VEGA ID
  OTTHUMG00000171902
• Locus Specific Databases
  • LRG_229

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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