TRAF3 Antibody
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Catalog numberF43379-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenTRAF3
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the TRAF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis TRAF3 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ13114
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PurityAntigen affinity
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DescriptionThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
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ImmunogenA portion of amino acids 490-517 from the human protein was used as the immunogen for this TRAF3 antibody.
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StorageAliquot the TRAF3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTRAF3
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Short nameAnti-TRAF3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to TRAF3
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Alternative techniqueantibodies
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Alternative to gene targetTNF receptor-associated factor 3, CAP-1 and CAP1 and CD40bp and CRAF1 and IIAE5 and LAP1, TRAF3 and IDBG-21240 and ENSG00000131323 and 7187, thioesterase binding, Plasma membranes, Traf3 and IDBG-172558 and ENSMUSG00000021277 and 22031, TRAF3 and IDBG-635183 and ENSBTAG00000013475 and 506182
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor associated factor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-05-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ring finger proteins
- Zinc fingers
- TNF receptor associated factors
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data