anti-TIM-1 Antibody

• Catalog number
  3809
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
• Gene names
  TIM-1 Antibody: TIM, KIM1, TIM1, HAVCR, KIM-1, TIM-1, TIMD1, TIMD-1, HAVCR-1, Hepatitis A virus cellular receptor 1, Kidney injury molecule 1, HAVcr-1
• Antibodie s label
  unlabelled serum
• Purity
  TIM-1 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TIM-1 antibody was made against a 16 amino acid synthetic peptide from near the amino terminus of human TIM-1.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TIM-1 antibody can be used for the detection of TIM-1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TIM-1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TIM-1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  153085427
• Ncbi nr
  NP_036338
• KDa
  40 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  26762
• GENE symbol
  HAVCR1
• Antigene name
  hepatitis A virus cellular receptor 1
• Source
  Homo sapiens
• Protein nr
  Q96D42
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TIM-1  
• Gene symbol
  TIMELESS, ARHGEF5, HAVCR1, HAVCR2, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
• Short name
  anti-TIM-1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTIM-1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11813
• Gene
  TIMELESS
• Long gene name
  timeless circadian regulator
• Synonyms gene name
  • timeless (Drosophila) homolog
  • timeless homolog (Drosophila)
• Synonyms
  • hTIM
  • TIM
  • TIM1
• Synonyms name
  • Tof1 homolog (S. cerevisiae)
  • timeless circadian clock 1
• GenBank acession
  • AF098162
• Locus
  12q13.3
• Discovery year
  1999-01-08
• Entrez gene record
  8914
• Pubmed identfication
  • 9856465
• RefSeq identity
  • NM_003920
• VEGA ID
  OTTHUMG00000170600

Gene info

• Identity
  HGNC:13209
• Gene
  ARHGEF5
• Long gene name
  Rho guanine nucleotide exchange factor 5
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 5
• Synonyms
  • TIM
  • TIM1
  • GEF5
  • P60
• Synonyms name
  • transforming immortalized mammary oncogene
  • guanine nucleotide regulatory protein TIM
  • ephexin3
• GenBank acession
  • U02082
• Locus
  7q35
• Discovery year
  2001-02-15
• Entrez gene record
  7984
• Pubmed identfication
  • 8134109
  • 7656213
• RefSeq identity
  • NM_005435
• Classification
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000158004

Gene info

• Identity
  HGNC:17866
• Gene
  HAVCR1
• Long gene name
  hepatitis A virus cellular receptor 1
• Synonyms
  • HAVCR-1
  • TIM-1
  • TIM1
  • HAVCR
  • TIMD1
  • CD365
  • KIM1
• Synonyms name
  • T-cell immunoglobulin mucin family member 1
  • kidney injury molecule 1
• GenBank acession
  • AF043724
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  26762
• Pubmed identfication
  • 9658108
  • 11725301
  • 18273441
• RefSeq identity
  • NM_012206
• Classification
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000163466

Gene info

• Identity
  HGNC:18437
• Gene
  HAVCR2
• Long gene name
  hepatitis A virus cellular receptor 2
• Synonyms
  • Tim-3
  • TIM3
  • FLJ14428
  • TIMD3
  • CD366
• Synonyms name
  • T-cell immunoglobulin mucin family member 3
• GenBank acession
  • AK027334
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  84868
• Pubmed identfication
  • 11823861
• RefSeq identity
  • NM_032782
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000130249

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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