anti-PUF60 Antibody

• Catalog number
  29-418
• Price
  Please ask
• Size
  100 ug

• Gene info
  PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
• Gene names
  PUF60, FIR, FLJ31379, RoBPI, SIAHBP1, VRJS
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PUF60.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  PUF60 antibody can be used for detection of PUF60 by ELISA at 1:62500. PUF60 antibody can be used for detection of PUF60 by western blot at 5.0 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PUF60 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  17298690
• Ncbi nr
  NP_055096
• KDa
  58 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  22827
• GENE symbol
  PUF60
• Antigene name
  poly-U binding splicing factor 60KDa
• Source
  Homo sapiens
• Protein nr
  Q9UHX1-2
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PUF60  
• Gene symbol
  PUF60
• Short name
  anti-PUF60 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPUF60 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  poly-U binding splicing factor 60KDa, FIR and RoBPI and SIAHBP1 and VRJS, PUF60 and IDBG-39284 and ENSG00000179950 and 22827, poly(A) RNA binding, multiple, Puf60 and IDBG-152633 and ENSMUSG00000002524 and 67959, BT.56130 and IDBG-643754 and ENSBTAG00000037493 and 512824

Gene info

• Identity
  HGNC:17042
• Gene
  PUF60
• Long gene name
  poly(U) binding splicing factor 60
• Synonyms gene name
  • poly(U) binding splicing factor 60KDa
• Synonyms
  • FIR
  • SIAHBP1
  • RoBPI
• Synonyms name
  • siah binding protein 1
  • FBP interacting repressor
  • pyrimidine tract binding splicing factor
  • Ro ribonucleoprotein binding protein 1
• GenBank acession
  • AF114818
• Locus
  8q24.3
• Discovery year
  2007-07-27
• Entrez gene record
  22827
• Pubmed identfication
  • 10668799
  • 10882074
  • 17579712
• RefSeq identity
  • NM_014281
• Classification
  • RNA binding motif containing
  • Spliceosomal A complex
• VEGA ID
  OTTHUMG00000165155

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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