-
Gene info
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
-
Gene names
PSMB2, HC7-I, MGC104215, MGC126885
-
Antibodie s label
unlabelled serum
-
Purity
Antibody is purified by peptide affinity chromatography method.
-
Ab raised in
Rabbit
-
Type
Polyclonal
-
Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMB2.
-
Immuno application
ELISA, Western Blot
-
Antibody advice
PSMB2 antibody can be used for detection of PSMB2 by ELISA at 1:312500. PSMB2 antibody can be used for detection of PSMB2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Suspention pH azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
-
Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PSMB2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
-
Works with
Human, Mouse, Rat
-
Omim nr
4506195
-
Ncbi nr
NP_002785
-
KDa
23 kDa
-
Vial with antibody
Lyophilized
-
Quantity per ml
1 mg/ml
-
NCBI GENE nr
5690
-
GENE symbol
PSMB2
-
Antigene name
proteasome (prosome, macropain) subunit, beta type, 2
-
Source
Homo sapiens
-
Protein nr
P49721
-
-
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
PSMB2
-
Short name
anti-PSMB2 Antibody
-
Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative name
Antibody toPSMB2 (antibody to-)
-
Alternative technique
antibodies
-
Alternative to gene target
proteasome (prosome, macropain) subunit, beta type, 2, HC7-I, PSMB2 and IDBG-96209 and ENSG00000126067 and 5690, protein binding, nuclei, Psmb2 and IDBG-189115 and ENSMUSG00000028837 and 26445, PSMB2 and IDBG-641505 and ENSBTAG00000002377 and 516919
-