anti-PMAIP1 Antibody

• Catalog number
  48-540
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Recently, a BH-3 only member of the Bcl-2 family have been identified in human and mouse and designated as Noxa (for damage). The expression of the Noxa gene involves direct activation of its promoter by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53-deficient thymocytes. Noxa cDNA codes for a 103-amino acid protein. The coimmunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl-2 family, such as, Bcl-XL and Mcl-1. Oda et al have also shown that blocking the endogenous Noxa induction results in the suppression of apoptosis. Treatment of cells with Noxa antisense oligonucleotides blocks radiation-induced apoptosis suggesting that Noxa may represent a mediator of p53-dependent apoptosis.
• Gene names
  PMAIP1, NOXA, PMA-induced protein 1, Protein Noxa, APR
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PMAIP1 antibody was made against amino acids 51 - 66 and 75-90 of PMAIP1 (Mouse).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  PMAimmunoprecipitation1 antibody can be used in immunohistochemistry starting at 20 ug/mL, and flow cytometry.
• Suspention pH azide
  PBS, 0.05% BSA, 0.05% sodium azide.
• Keep at
  PMAIP1 antibody should be stored long term (months) at -20 grades C and short term (weeks) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  6919841
• Ncbi nr
  Q13794
• Vial with antibody
  in solution
• NCBI GENE nr
  5366
• GENE symbol
  PMAIP1
• Antigene name
  phorbol-12-myristate-13-acetate-induced protein 1
• Source
  Homo sapiens
• Protein nr
  Q13794
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PMAIP1  
• Gene symbol
  PMAIP1
• Short name
  anti-PMAIP1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody tophorbol-12-myristate-13-acetate-induced protein 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  phorbol-12-myristate-13-acetate-induced protein 1, APR and NOXA, PMAIP1 and IDBG-4142 and ENSG00000141682 and 5366, protein binding, nuclei, Pmaip1 and IDBG-155006 and ENSMUSG00000024521 and 58801

Gene info

• Identity
  HGNC:9108
• Gene
  PMAIP1
• Long gene name
  phorbol-12-myristate-13-acetate-induced protein 1
• Synonyms
  • APR
  • NOXA
• GenBank acession
  • D90070
• Locus
  18q21.32
• Discovery year
  1991-08-12
• Entrez gene record
  5366
• Pubmed identfication
  • 2398525
  • 12879012
• RefSeq identity
  • NM_021127
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000132765

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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