GOAT ANTI HUMAN NOXA

• Catalog number
  MBS224213
• Price
  780.81 USD
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [NOXA]
• Other_names
  [phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; adult T cell leukemia-derived PMA-responsive; immediate-early-response protein APR; protein Noxa; phorbol-12-myristate-13-acetate-induced protein 1; Immediate-early-response protein APR; Protein Noxa]
• Products_gene_name
  [NOXA]
• Other_gene_names
  [PMAIP1; PMAIP1; APR; NOXA; NOXA; PMA-induced protein 1]
• Clonality
  Polyclonal
• Specificity
  This item specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, and acts as promoter of caspase and apoptosis activation. Noxa is a transcriptional target of p53, p73 and BH3-only proteins, and competes with, and displaces, the proapoptotic proteins BAK1, and BIM, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), thereby influencing apoptosis versus cell survival.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Latin name
  Capra aegagrus hircus
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  NOXA  
• Gene symbol
  PMAIP1
• Short name
  GOAT ANTI NOXA
• Technique
  anti human, anti, Goat, antibody to, anti human antibodies, goats
• Host
  Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
• Isotype
  IgG
• Species
  Human, Goats, Humans
• Alternative name
  caprine antibody to H. sapiens NOXA
• Alternative technique
  antibodies, caprine

Gene info

• Identity
  HGNC:9108
• Gene
  PMAIP1
• Long gene name
  phorbol-12-myristate-13-acetate-induced protein 1
• Synonyms
  • APR
  • NOXA
• GenBank acession
  • D90070
• Locus
  18q21.32
• Discovery year
  1991-08-12
• Entrez gene record
  5366
• Pubmed identfication
  • 2398525
  • 12879012
• RefSeq identity
  • NM_021127
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000132765

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products