anti-MER Antibody [7E5G1]

• Catalog number
  32-192
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
• Gene names
  MER, Proto-oncogene c-MerMER, RP38, c-mer
• Antibodie s label
  unlabelled serum
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  7E5G1
• Immunoglobulin
  IgG1
• Antigen
  Ni-NTA purified full-length recombinant MER-His expressed in E. Coli strain BL21 (DE3).
• Immuno application
  ELISA, Western Blot
• Antibody advice
  Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
• Suspention pH azide
  Ascitic fluid containing 0.03% sodium azide.
• Keep at
  MER monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  160332297
• Ncbi nr
  Q12866
• NCBI GENE nr
  10461
• GENE symbol
  MERTK
• Antigene name
  c-mer proto-oncogene tyrosine kinase
• Source
  Homo sapiens
• Protein nr
  Q12866
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MER   [7E5G1]  
• Gene symbol
  MERTK
• Short name
  anti-MER Antibody [7E5G1]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMER (antibody to-) [7E5G1]
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7027
• Gene
  MERTK
• Long gene name
  MER proto-oncogene, tyrosine kinase
• Synonyms gene name
  • c-mer proto-oncogene tyrosine kinase
• Synonyms
  • mer
  • RP38
  • c-Eyk
  • Tyro12
• GenBank acession
  • U08023
• Locus
  2q13
• Discovery year
  1998-11-30
• Entrez gene record
  10461
• Pubmed identfication
  • 8086340
  • 10343112
• Classification
  • Receptor tyrosine kinases
  • Fibronectin type III domain containing
  • I-set domain containing
• VEGA ID
  OTTHUMG00000131278
• Locus Specific Databases
  • Mutations of the MER Receptor Tyrosine Kinase Gene

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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