anti-HMGB2 Antibody

• Catalog number
  27-448
• Price
  Please ask
• Size
  50 ug

• Gene info
  This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V (D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Gene names
  HMGB2, HMG2
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HMGB2.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  HMGB2 antibody can be used for detection of HMGB2 by ELISA at 1:312500. HMGB2 antibody can be used for detection of HMGB2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store HMGB2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  11321591
• Ncbi nr
  NP_002120
• KDa
  24 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  3148
• GENE symbol
  HMGB2
• Antigene name
  high mobility group box 2
• Source
  Homo sapiens
• Protein nr
  P26583
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HMGB2  
• Gene symbol
  HMGB2
• Short name
  anti-HMGB2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toHMGB2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  high mobility group box 2, HMG2, HMGB2 and IDBG-44657 and ENSG00000164104 and 3148, DNA binding, nuclei, Hmgb2 and IDBG-156235 and ENSMUSG00000054717 and 97165, HMGB2 and IDBG-629304 and ENSBTAG00000015101 and 540444,618297

Gene info

• Identity
  HGNC:5000
• Gene
  HMGB2
• Long gene name
  high mobility group box 2
• Synonyms gene
  • HMG2
• Synonyms gene name
  • high-mobility group (nonhistone chromosomal) protein 2
  • high-mobility group box 2
• Locus
  4q34.1
• Discovery year
  1993-12-13
• Entrez gene record
  3148
• Pubmed identfication
  • 1754403
• RefSeq identity
  • NM_001130688
• Classification
  • Canonical high mobility group
  • SET complex
• VEGA ID
  OTTHUMG00000160799

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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