anti-HAX1 Antibody

• Catalog number
  26-634
• Price
  Please ask
• Size
  50 ug

• Gene info
  HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
• Gene names
  HAX1, HCLSBP1, HS1BP1, SCN3
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAX1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  HAX1 antibody can be used for detection of HAX1 by ELISA at 1:62500. HAX1 antibody can be used for detection of HAX1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store HAX1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse
• Omim nr
  13435356
• Ncbi nr
  NP_006109
• KDa
  31 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  10456
• GENE symbol
  HAX1
• Antigene name
  HCLS1 associated protein X-1
• Source
  Homo sapiens
• Protein nr
  O00165
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HAX1  
• Gene symbol
  HAX1
• Short name
  anti-HAX1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toHAX1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  HCLS1 associated protein X-1, HCLSBP1 and HS1BP1 and SCN3, HAX1 and IDBG-102924 and ENSG00000143575 and 10456, protein N-terminus binding, nuclei, Hax1 and IDBG-165357 and ENSMUSG00000027944 and 23897, HAX1 and IDBG-632533 and ENSBTAG00000013025 and 506895

Gene info

• Identity
  HGNC:16915
• Gene
  HAX1
• Long gene name
  HCLS1 associated protein X-1
• Synonyms
  • HS1BP1
  • HCLSBP1
  • HAX-1
• Synonyms name
  • HCLS1 (and PKD2) associated protein
• GenBank acession
  • U68566
• Locus
  1q21.3
• Discovery year
  2005-05-19
• Entrez gene record
  10456
• Pubmed identfication
  • 9058808
  • 10760273
• RefSeq identity
  • NM_006118
• VEGA ID
  OTTHUMG00000035978
• Locus Specific Databases
  • HAX1base: Mutation registry for severe congenital neutropenia (Kostmann disease)
  • LRG_64

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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