anti-Disp2 Antibody
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Catalog number4883
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoDisp2 Antibody: Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the Disp proteins have been implicated in these pathways. Recently, it has been shown that Disp2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased Disp2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by Disp2 mutants. At least two isoforms of Disp2 are known to exist. This Disp2 antibody is predicted to not cross-react with Disp1 or Disp3.
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Gene namesDisp2 Antibody: DISPB, HsT16908, DISPB, KIAA1742, Protein dispatched homolog 2
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Antibodie s labelunlabelled serum
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PurityDisp2 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenDisp2 antibody was made against a 19 amino acid synthetic peptide from near the carboxy terminus of human Disp2.
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Immuno applicationELISA, Western Blot
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Antibody adviceDisp2 antibody can be used for the detection of Disp2 by Western blot at 1 - 2 ug/mL.
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Suspention pH azideDisp2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atDisp2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr160380692
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Ncbi nrA7MBM2
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr85455
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GENE symbolDISP2
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Antigene namedispatched homolog 2 (Drosophila)
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SourceHomo sapiens
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Protein nrA7MBM2
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDISP2
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Short nameanti-Disp2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDisp2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namedispatched RND transporter family member 2
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Synonyms gene
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Synonyms gene name
- dispatched homolog 2 (Drosophila)
- long intergenic non-protein coding RNA 594
- chromosome 15 open reading frame 36
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data