DISP2 Antibody

• Catalog number
  bs-11588R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DISP2 Primary Polyclonal Antibody
• Also known as
  DISP2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DISP2
• Specificity
  This is a highly specific antibody against DISP2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1150-1200/1401
• Subcellular location
  Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DISP2
• Gene ID number
  85455
• Swiss Prot
  A7MBM2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DISPB; HsT16908; Protein dispatched homolog 2; DISP2; KIAA1742
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DISP2  
• Gene symbol
  DISP2
• Short name
  Anti-DISP2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DISP2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19712
• Gene
  DISP2
• Long gene name
  dispatched RND transporter family member 2
• Synonyms gene
  • LINC00594
  • C15orf36
• Synonyms gene name
  • dispatched homolog 2 (Drosophila)
  • long intergenic non-protein coding RNA 594
  • chromosome 15 open reading frame 36
• Synonyms
  • DISPB
  • KIAA1742
  • HsT16908
• GenBank acession
  • AB051529
• Locus
  15q15.1
• Discovery year
  2003-12-12
• Entrez gene record
  85455
• Pubmed identfication
  • 11214970
  • 10619433
• RefSeq identity
  • NM_033510
• VEGA ID
  OTTHUMG00000129983

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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