anti-CRKL Antibody

• Catalog number
  31-010
• Price
  Please ask
• Size
  50 ug

• Gene info
  CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
• Gene names
  CRKL,
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRKL.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CRKL antibody can be used for detection of CRKL by ELISA at 1:62500. CRKL antibody can be used for detection of CRKL by western blot at 2 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store CRKL antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  4885153
• Ncbi nr
  NP_005198
• KDa
  34 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  1399
• GENE symbol
  CRKL
• Antigene name
  v-crk avian sarcoma virus CT10 oncogene homolog-like
• Source
  Homo sapiens
• Protein nr
  P46109
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CRKL  
• Gene symbol
  CRKL
• Short name
  anti-CRKL Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCRKL (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  v-crk sarcoma virus CT10 oncogene homolog (avian)-like, CRKL and IDBG-1833 and ENSG00000099942 and 1399, poly(A) RNA binding, Cytoplasm, Crkl and IDBG-138913 and ENSMUSG00000006134 and 12929, CRKL and IDBG-637664 and ENSBTAG00000045548 and

Gene info

• Identity
  HGNC:2363
• Gene
  CRKL
• Long gene name
  CRK like proto-oncogene, adaptor protein
• Synonyms gene name
  • v-crk avian sarcoma virus CT10 oncogene homolog-like
• Locus
  22q11.21
• Discovery year
  1994-09-14
• Entrez gene record
  1399
• Pubmed identfication
  • 8361759
  • 8798523
• RefSeq identity
  • NM_005207
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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