anti-CCR8 Antibody
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Catalog number31-087
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PricePlease ask
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Size100 ug
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Gene infoCCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.
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Gene namesCCR8, CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by protein A chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCR8.
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Immuno applicationELISA, Western Blot
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Antibody adviceCCR8 antibody can be used for detection of CCR8 by ELISA at 1:62500. CCR8 antibody can be used for detection of CCR8 by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store CCR8 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr4885121
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Ncbi nrNP_005192
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KDa41 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr1237
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GENE symbolCCR8
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Antigene namechemokine (C-C motif) receptor 8
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SourceHomo sapiens
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Protein nrP51685
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCCR8
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Short nameanti-CCR8 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toCCR8 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-C motif) receptor 8, CC-CKR-8 and CCR-8 and CDw198 and CKRL1 and CMKBR8 and CMKBRL2 and CY6 and GPRCY6 and TER1, CCR8 and IDBG-26700 and ENSG00000179934 and 1237, C-C chemokine receptor activity, Plasma membranes, Ccr8 and IDBG-205018 and ENSMUSG00000042262 and 12776, BT.30825 and IDBG-647797 and ENSBTAG00000015483 and 407772
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Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine receptor 8
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Synonyms gene
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Synonyms gene name
- chemokine (C-C motif) receptor 8
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
