CCR8 Antibody

• Catalog number
  bs-1679R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CCR8 Primary Polyclonal Antibody
• Also known as
  CCR8 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CCR8
• Specificity
  This is a highly specific antibody against CCR8.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from mouse CCR-8
• Gene ID number
  1237
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C-C chemokine receptor 8; C-C chemokine receptor type 8;CCR-8; C-C CKR-8; CC-CKR-8; CCR8; CD_antigen=CDw198.GPR-CY6; GPRCY6; Chemokine receptor-like 1; CKR-L1; TER1; CMKBRL2; CC-chemokine receptor CHEMR1; CMKBR8; CKRL1; CCR8_MOUSE.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR8  
• Gene symbol
  CCR8
• Short name
  Anti-CCR8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CCR8 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 8, CC-CKR-8 and CCR-8 and CDw198 and CKRL1 and CMKBR8 and CMKBRL2 and CY6 and GPRCY6 and TER1, CCR8 and IDBG-26700 and ENSG00000179934 and 1237, C-C chemokine receptor activity, Plasma membranes, Ccr8 and IDBG-205018 and ENSMUSG00000042262 and 12776, BT.30825 and IDBG-647797 and ENSBTAG00000015483 and 407772

Gene info

• Identity
  HGNC:1609
• Gene
  CCR8
• Long gene name
  C-C motif chemokine receptor 8
• Synonyms gene
  • CMKBRL2
  • CMKBR8
• Synonyms gene name
  • chemokine (C-C motif) receptor 8
• Synonyms
  • CY6
  • TER1
  • CKR-L1
  • GPR-CY6
  • CDw198
• GenBank acession
  • D49919
• Locus
  3p22.1
• Discovery year
  1997-04-21
• Entrez gene record
  1237
• Pubmed identfication
  • 8816377
  • 8886020
• RefSeq identity
  • NM_005201
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000131290

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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