anti-Caspase-7 Antibody

• Catalog number
  3465
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Caspase-7 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.
• Gene names
  Caspase-7 Antibody: MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3, MCH3, Caspase-7, Apoptotic protease Mch-3
• Antibodie s label
  unlabelled serum
• Purity
  Caspase-7 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Depending on cell lines or tissues used, other cleavage products may be observed.
• Antigen
  Caspase-7 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human Caspase-7.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  Casp-7 antibody can be used for the detection of Caspase-7 by Western blot at 0.5 to 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2 ug/mL.
• Suspention pH azide
  Caspase-7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Caspase-7 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  1730092
• Ncbi nr
  P55210
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  840
• GENE symbol
  CASP7
• Antigene name
  caspase 7, apoptosis-related cysteine peptidase
• Source
  Homo sapiens
• Protein nr
  P55210
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Caspase-7  
• Gene symbol
  CASP7, MZB1
• Short name
  anti-Caspase-7 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCasp-7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1508
• Gene
  CASP7
• Long gene name
  caspase 7
• Synonyms gene name
  • caspase 7, apoptosis-related cysteine protease
  • caspase 7, apoptosis-related cysteine peptidase
• Synonyms
  • MCH3
  • CMH-1
  • ICE-LAP3
• GenBank acession
  • U37448
• Locus
  10q25.3
• Discovery year
  1996-07-22
• Entrez gene record
  840
• Pubmed identfication
  • 8521391
  • 8576161
• RefSeq identity
  • NM_033338
• Classification
  • Caspases
• VEGA ID
  OTTHUMG00000019076

Gene info

• Identity
  HGNC:30125
• Gene
  MZB1
• Long gene name
  marginal zone B and B1 cell specific protein
• Synonyms gene name
  • marginal zone B and B1 cell-specific protein
• Synonyms
  • PACAP
  • MGC29506
  • HSPC190
  • pERp1
  • MEDA-7
• Synonyms name
  • plasma cell-induced ER protein 1
  • proapoptotic caspase adaptor protein
  • mesenteric oestrogen-dependent adipose gene- 7
• GenBank acession
  • AF151024
• Locus
  5q31.2
• Discovery year
  2012-09-19
• Entrez gene record
  51237
• Pubmed identfication
  • 22573353
  • 12573802
  • 11350957
  • 21093319
  • 21688198
• RefSeq identity
  • NM_016459
• VEGA ID
  OTTHUMG00000163390

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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