anti-BLK Antibody [9D10B7H6 / 9D10A8F8]

• Catalog number
  32-118
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
• Gene names
  B lymphocyte kinaseMODY11
• Antibodie s label
  unlabelled serum
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  9D10B7H6 / 9D10A8F8
• Immunoglobulin
  IgG1
• Antigen
  Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000IHC(F):1:500 - 1:2,000ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
• Suspention pH azide
  Ascitic fluid containing 0.03% sodium azide.
• Keep at
  BLK monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  158936749
• Ncbi nr
  P51451
• NCBI GENE nr
  640
• GENE symbol
  BLK
• Antigene name
  B lymphoid tyrosine kinase
• Source
  Homo sapiens
• Protein nr
  P51451
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BLK   [9D10B7H6   9D10A8F8]  
• Gene symbol
  BLK
• Short name
  anti-BLK Antibody [9D10B7H6 / 9D10A8F8]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toBLK (antibody to-) [9D10B7H6 / 9D10A8F8]
• Alternative technique
  antibodies
• Alternative to gene target
  B lymphoid tyrosine kinase, MODY11, BLK and IDBG-7345 and ENSG00000136573 and 640, transferase activity, Plasma membranes, Blk and IDBG-172522 and ENSMUSG00000014453 and 12143, BLK and IDBG-629427 and ENSBTAG00000005049 and 532587

Gene info

• Identity
  HGNC:1057
• Gene
  BLK
• Long gene name
  BLK proto-oncogene, Src family tyrosine kinase
• Synonyms gene name
  • B lymphoid tyrosine kinase
• Synonyms
  • MGC10442
• GenBank acession
  • BC004473
• Locus
  8p23.1
• Discovery year
  1995-05-17
• Entrez gene record
  640
• Pubmed identfication
  • 7845672
• Classification
  • SH2 domain containing
  • Src family tyrosine kinases
• VEGA ID
  OTTHUMG00000090729

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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