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APOC1 Rabbit pAb

CAT: 0855-ES18289-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES18289-01Size:50 µL
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Background
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Description
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016],
Product Name Alternative
Apolipoprotein C-I (Apo-CIB; ApoC-IB; Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB'; ApoC-IB') ]
UniProt
P02654
Swiss Prot
P02654
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human APOC1 AA range: 1-50
Target
APOC1
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA (peptide) 1:5000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted .
Other Product Names
Apolipoprotein C-I (Apo-CIB; ApoC-IB; Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB'; ApoC-IB') ]
Gene ID (Human)
341

UniProtKB · P02654

Apolipoprotein C-I

APOC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02654
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APOC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Apo-CI, ApoC-I
EC number
—
Processing
Precursor
Secondary accessions
B2R526, Q6IB97
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Lipid transportTransport

Cellular component

SecretedVLDL

Domain

Signal

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