Levomefolic acid

• UNSPSC Description:

  Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[1][2].

• Target Antigen:

  DNA/RNA Synthesis; Endogenous Metabolite; Reactive Oxygen Species

• Type:

  Natural Products

• Related Pathways:

  Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/Levomefolic-acid.html

• Solubility:

  DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 2.08 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NC[C@@H]2N(C)C3=C(NC(N)=NC3=O)NC2)C=C1)=O

• Molecular Weight:

  459.46

• References & Citations:

  [1]Manisha Prajapat, et al. Virtual screening and molecular dynamics study of approved drugs as inhibitors of spike protein S1 domain and ACE2 interaction in SARS-CoV-2. J Mol Graph Model. 2020 Dec;101:107716.|[2] Maša Vidmar Golja, et al. Simultaneous quantification of intracellular concentrations of clinically important metabolites of folate-homocysteine cycle by LC-MS/MS. Anal Biochem. 2020 Sep 15;605:113830.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Launched

• CAS Number:

  31690-09-2