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Benralizumab

CAT: 0804-HY-P9923-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P9923-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα) -directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma[1].
CAS Number
1044511-01-4
Product Name Alternative
MEDI-563; BIW-8405; KHK4563
UNSPSC
12352203
Target
Apoptosis; Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/benralizumab.html
Purity
99.1
Solubility
H2O
Smiles
[Benralizumab]
Molecular Weight
(146.06 kDa)
References & Citations
[1]Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019 Sep 25;5 (3) . pii: 00009-2019.|[2]Kolbeck R, et al. MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function. J Allergy Clin Immunol. 2010 Jun;125 (6) :1344-1353.e2.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Isoform
IL-5

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