Products for Research Use Only
RegisterLogin

Monotropein (Standard)

CAT: 0804-HY-N0648RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0648RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS) -induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin -induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury[1][2][3].
CAS Number
5945-50-6
UNSPSC
12352005
Target
Apoptosis; Heme Oxygenase (HO) ; Interleukin Related; Keap1-Nrf2; NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/monotropein-standard.html
Smiles
O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H]2[C@@]([C@@]3(O)CO)([H])[C@@](C=C3)([H])C(C(O)=O)=CO2
Molecular Formula
C16H22O11
Molecular Weight
390.34
References & Citations
[1]Wang F, et al.Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes.Int Immunopharmacol. 2014 Dec;23 (2) :575-80.|[2]Zhang, Y., et al., (2020) . The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 129, 110408.|[3]Gong, Y., & Wang, J. (2023) . Monotropein alleviates sepsis-elicited acute lung injury via the NF-κB pathway. The Journal of pharmacy and pharmacology, 75 (9), 1249–1258.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-N0648-01Monotropein
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)
HY-N3373RLoganetin (Standard)

Alternative Products

CatalogName
MBS3840497-01Monotropein
A14650-25Monotropein 25mg
A14650-20Monotropein 20mg
A14650-10Monotropein 10mg
371696Monotropein discontinued
A14650-5Monotropein 5mg
A14650-10mM-DMonotropein 10mM * 1mL in DMSO
abx098968-01Standard

Popular Products