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Gamma-DGG (acetate)

CAT: 0804-HY-100785A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100785A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gamma-DGG acetate (γDGG acetate) is a competitive AMPA receptor blocker. gamma-DGG acetate is also a reversible Excitatory post-synaptic potentials (e.p.s.p.s) antagonist[1][2].
CAS Number
2935387-13-4
Product Name Alternative
γDGG (acetate) ; γ-D-Glutamylglycine (acetate)
UNSPSC
12352211
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gamma-dgg-acetate.html
Smiles
CC(O)=O.OC(CNC(CC[C@@H](N)C(O)=O)=O)=O
Molecular Formula
C9H16N2O7
Molecular Weight
264.23
References & Citations
[1]Wu XS, et al. The origin of quantal size variation: vesicular glutamate concentration plays a significant role. J Neurosci. 2007 Mar 14;27 (11) :3046-56.|[2]Crunelli V, et al. Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus. J Physiol. 1983 Aug;341:627-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

gamma-DGG acetate(6729-55-1 free base)
CAS Number2935387-13-4
PubChem CID156598975
IUPAC Nameacetic acid;(2R)-2-amino-5-(carboxymethylamino)-5-oxopentanoic acid
Molecular FormulaC9H16N2O7
Molecular Weight264.23
Topological Polar Surface Area167
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Heavy Atom Count18
Formal Charge0
Complexity271
SMILES
CC(=O)O.C(CC(=O)NCC(=O)O)[C@H](C(=O)O)N
InChI
InChI=1S/C7H12N2O5.C2H4O2/c8-4(7(13)14)1-2-5(10)9-3-6(11)12;1-2(3)4/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14);1H3,(H,3,4)/t4-;/m1./s1
InChIKey
LVLYMXYYOGBGBJ-PGMHMLKASA-N
Chemical Structure
2D Structure
2D structure of gamma-DGG acetate(6729-55-1 free base)
CAS: 2935387-13-4
CID: 156598975
Formula: C9H16N2O7
MW: 264.23
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight264.23
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass264.09575085
Monoisotopic Mass264.09575085
Topological Polar Surface Area167 Ų
Heavy Atom Count18
Formal Charge0
Complexity271
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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